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Cat No. | Product Name | Synonyms | Targets |
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T11337 | Fumarate hydratase-IN-1 | Mitochondrial Metabolism | |
Fumarate hydratase-IN-1 is a cell-permeable fumarate hydratase inhibitor with antiproliferative activity and can be used to study cellular activity. | |||
T11336 | Fumarate hydratase-IN-2 sodium salt | Others | |
Fumarate hydratase-IN-2 sodium salt (compound 3) is a cell-permeable and competitive fumarate hydratase inhibitor ( K i =4.5 μM). Fumarate hydratase-IN-2 sodium salt has nutrient-dependent cytotoxicity [1]. | |||
T71901 | MP-1 | ||
MP-1 is a covalent inhibitor of fumarate hydratase (FH) that exhibits cytotoxicity dependent on FH. MP-1 engages a functional cysteine in the Zn-finger domain of the tRNA methyltransferase enzyme TRMT1. |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-02003 | FH/Fumarate Hydratase Protein, Human, Recombinant (His) | Human | E. coli |
Fumarate Hydratase (FH) is an enzymatic component of the tricarboxylic acid (TCA) cycle, or Krebs cycle, and catalyzes the formation of L-malate from fumarate. It exists in both a cytosolic form and an N-terminal extende... | |||
TMPJ-00313 | Fumarase Protein, Human, Recombinant | Human | E. coli |
Fumarase is an enzyme that catalyze the reversible hydration/dehydration of fumarate to S-malate and is involved in the tricarboxylic acid or Krebs cycle. Fumarase exists in both form, cytosolic formand N-terminal extend... |